The LACTB2 Polyclonal Antibody (PAC036242) is a vital tool for researchers studying LACTB2, a mitochondrial protein involved in lipid metabolism and cell homeostasis. This antibody, generated in rabbits, exhibits high specificity for human samples and is validated for use in applications such as Western blotting. It binds to the LACTB2 protein, enabling accurate detection and analysis in various cell types, making it an invaluable resource for investigations in metabolic and cellular biology.LACTB2, also known as a lactamase beta-2 protein, plays a crucial role in lipid metabolism and mitochondrial function, making it a promising target for research in metabolic diseases, cancer, and aging.
Understanding the functions and regulation of LACTB2 is essential for unraveling its impact on cellular processes and potential implications for disease development. The LACTB2 Polyclonal Antibody offers researchers a reliable tool to explore the intricate roles of LACTB2 in cellular metabolism and disease progression.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO36242 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO36242 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO36242 at dilution of 1:100.
Background:
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
Synonyms:
Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2), LACTB2
UniProt Protein Function:
LACTB2: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.Protein type: Hydrolase; EC 3.-.-.-; MitochondrialChromosomal Location of Human Ortholog: 8q13.3Cellular Component: mitochondrionMolecular Function: hydrolase activity; metal ion bindingBiological Process: metabolic process
