The KRT33B Polyclonal Antibody (PACO10168) is a valuable tool for researchers studying keratin 33B, a type I hair keratin protein found in the hair follicle. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.Keratin 33B is important for maintaining the structural integrity of hair fibers and is implicated in hair disorders and diseases. This antibody binds specifically to KRT33B, allowing for the detection and analysis of this protein in different cell types.
Its application in research on hair biology, dermatology, and hair conditions makes it an essential reagent for understanding the role of keratin 33B in hair growth and health.By utilizing the KRT33B Polyclonal Antibody in your experiments, you can further investigate the function and regulation of keratin 33B, leading to potential insights into hair development, disorders, and therapeutic strategies for conditions affecting hair follicles.
KRT33B: a member of the keratin gene family. This gene is one of multiple type I hair keratin genes that are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, the encoded protein is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, keratin 33A and keratin 33B. [provided by RefSeq, May 2012]Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 17q21.2Cellular Component: extracellular spaceMolecular Function: protein bindingBiological Process: aging; hair cycle
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the keratin gene family. This gene is one of multiple type I hair keratin genes that are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, the encoded protein is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, keratin 33A and keratin 33B. [provided by RefSeq, May 2012]
