The CHCHD3 Polyclonal Antibody (CAB19959) is a valuable tool for researchers studying CHCHD3, a protein involved in mitochondrial function and regulation. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it perfect for Western blot applications. By targeting the CHCHD3 protein, this antibody allows for the detection and analysis of CHCHD3 in various cell types, making it ideal for research in the fields of molecular biology and mitochondrial dysfunction.CHCHD3 is a key player in maintaining mitochondrial integrity and function, making it a crucial target for studying mitochondrial diseases and disorders.
Research on CHCHD3 can provide valuable insights into mitochondrial dysfunction, oxidative stress, and their roles in various diseases, including neurodegenerative disorders and metabolic syndromes. By understanding the function and regulation of CHCHD3, researchers can develop new therapies and interventions to target mitochondrial-related pathologies.
Product Name:
[KO Validated] CHCHD3 Rabbit Polyclonal Antibody
SKU:
CAB19959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human CHCHD3 (NP_060282.1).
The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
54927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CHCHD3 knockout (KO) 293T cells, using [KO Validated] CHCHD3 Rabbit pAb (CAB19959) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
