The KO-KD Validated MYD88 Rabbit Monoclonal Antibody is a powerful tool for researchers studying MYD88, a critical adaptor protein in the innate immune response pathway. This antibody, validated for knockout and knockdown experiments, is highly specific to human samples and is well-suited for use in techniques such as Western blot and immunofluorescence.MYD88 is known for its role in signaling pathways involved in inflammation and immune response, making it a target of interest in studies on inflammatory diseases, autoimmune disorders, and cancer. By using the KO-KD Validated MYD88 Rabbit Monoclonal Antibody, researchers can accurately assess MYD88 expression levels in various cell types, contributing to a better understanding of its function and potential therapeutic implications.
This antibody offers high sensitivity and specificity in detecting MYD88 protein, providing researchers with reliable results for their experiments in immunology and cancer research. By targeting MYD88, researchers can gain valuable insights into the molecular mechanisms underlying immune response and inflammation, paving the way for innovative therapeutic approaches in the treatment of various diseases.
Product Name:
[KO/KD Validated]MyD88 Rabbit Monoclonal Antibody
SKU:
CAB22600
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human MyD88 (NP_002459.3).
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
4615
Clone Number:
ARC52507_ARC52509
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MyD88 Rabbit PolymAb® (CAB22600) at 1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
![[KO/KD Validated]MyD88 Rabbit Monoclonal Antibody (CAB22600)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/223322/583859/kokd-validatedmyd88-rabbit-monoclonal-antibody__09830.1701185497.jpg?c=2&imbypass=on "[KO/KD Validated]MyD88 Rabbit Monoclonal Antibody (CAB22600)")
