The KLK11 Polyclonal Antibody (CAB12565) is a powerful tool for researchers studying KLK11, a member of the kallikrein-related peptidase family known for its role in cancer progression and metastasis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for Western blot applications.KLK11, also known as Kallikrein-related peptidase 11, is a serine protease that has been associated with various types of cancer, including breast, ovarian, and prostate cancer. By targeting KLK11 with this antibody, researchers can better understand its function and regulation in cancer cells, paving the way for the development of novel therapeutic strategies.
Investigating the expression and activity of KLK11 using the CAB12565 antibody holds great promise for advancing our knowledge of cancer biology and potentially identifying new targets for anti-cancer therapies. This antibody is a valuable tool for studies focused on elucidating the role of KLK11 in tumor progression and metastasis, ultimately contributing to the advancement of precision medicine in oncology.
Product Name:
KLK11 Rabbit Polyclonal Antibody
SKU:
CAB12565
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human KLK11 (NP_001129504.1).
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed.
Purification Method:
Affinity purification
Gene ID:
11012
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 22Rv1 cells, using KLK11 Rabbit pAb (CAB12565) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 20s.
