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KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)

SKU:
CPAB0510
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P5F2AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)

The KIR2DS4 Polyclonal Antibody (CPAB0510) is a valuable tool for researchers studying the KIR2DS4 protein, a member of the killer cell immunoglobulin-like receptor (KIR) family. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.KIR2DS4 is a cell surface receptor involved in the regulation of natural killer (NK) cell function and immune response. It has been linked to the recognition and elimination of infected or cancerous cells by the immune system. The KIR2DS4 Polyclonal Antibody binds specifically to the KIR2DS4 protein, allowing for accurate detection and analysis in a variety of cell types.

Research on KIR2DS4 is essential for understanding its role in immune surveillance and response to pathogens and tumors. By investigating the function and expression of KIR2DS4, scientists can gain insights into its potential as a target for immunotherapy in diseases such as cancer and viral infections. The KIR2DS4 Polyclonal Antibody is a valuable tool for studies in immunology, oncology, and infectious diseases.

Product Name:KIR2DS4 Antibody
Product Sku:CPAB0510
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KIR2DS4 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KIR2DS4 purified from Ecoli.
Clone:P5F2AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:KIR2DS4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. The KIR genes are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes.
Synonyms:Killer cell immunoglobulin-like receptor 2DS4, MHC class I NK cell receptor, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clone CL-39, p58 NK receptor, CL-17, CD158 antigen-like family member I, CD158i antigen, KIR2DS4, CD158I, KKA3, NKAT8, KIR1D, KIR412, MGC120019, MGC125315, MGC125317.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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