The KIFAP3 Rabbit Monoclonal Antibody (CAB5216) is a cutting-edge tool for researchers studying KIFAP3, a key protein involved in intracellular transport processes within cells. This high-quality antibody, developed using rabbits, is specifically designed for use in experiments targeting KIFAP3 in human samples.With its superior reactivity and specificity, this antibody is ideal for applications such as Western blotting and immunohistochemistry, enabling accurate detection and analysis of KIFAP3 in various cell types. Its reliability and consistency make it a valuable asset for studies in cell biology, neuroscience, and cancer research.
KIFAP3, a kinesin-like protein, plays a crucial role in cellular functions such as vesicle transport and organelle movement. Understanding the function and regulation of KIFAP3 is essential for unraveling its impact on cellular processes and its potential implications in disease development. This antibody provides researchers with a powerful tool to investigate the role of KIFAP3 in health and disease, paving the way for new discoveries and insights in the field of molecular biology.
Product Name:
KIFAP3 Rabbit Monoclonal Antibody
SKU:
CAB5216
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 675-792 of human KIFAP3 (Q92845).
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22920
Clone Number:
ARC1211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KIFAP3 Rabbit mAb (CAB5216) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
