The KCNS3 Polyclonal Antibody (CAB7906) is designed for research involving KCNS3, a potassium channel subunit believed to play a role in regulating the electrical activity of neurons. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the KCNS3 protein, this antibody enables the detection and analysis of KCNS3 in various cell types, making it ideal for studies in neuroscience and neurology.KCNS3, also known as Kv9.3, is crucial in modulating neuronal excitability and synaptic transmission, making it a potential target for research into neurological disorders such as epilepsy, Alzheimer's disease, and Parkinson's disease.
Understanding the function of KCNS3 can provide insights into the pathophysiology of these conditions and may lead to the development of novel therapeutic strategies aimed at modulating potassium channel activity in the brain.Overall, the KCNS3 Polyclonal Antibody (CAB7906) is a valuable tool for researchers interested in exploring the role of KCNS3 in neuronal function and dysfunction, offering new insights into the mechanisms underlying neurological diseases and potential targets for therapeutic intervention.
Product Name:
KCNS3 Rabbit Polyclonal Antibody
SKU:
CAB7906
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KCNS3 (NP_002243.3).
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3790
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNS3 Rabbit pAb (CAB7906) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
