The KCNH6 Polyclonal Antibody (CAB15522) is a valuable research tool for studying the KCNH6 protein, a member of the voltage-gated potassium channel family. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the KCNH6 protein, this antibody allows for the accurate detection and analysis of KCNH6 expression in a variety of cell types.KCNH6, also known as the Ether-Ã -go-go homolog 2 (EAG2) channel, plays a crucial role in regulating neuronal excitability and neurotransmitter release.
Dysregulation of KCNH6 has been linked to neurological disorders such as epilepsy and Parkinson's disease, making it an important target for research in neuroscience and drug development. By studying the function of KCNH6, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new treatment strategies.
Product Name:
KCNH6 Rabbit Polyclonal Antibody
SKU:
CAB15522
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1).
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
81033
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using KCNH6 Rabbit pAb (CAB15522) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
