IRF1 Rabbit Polyclonal Antibody (CAB7692)
- SKU:
- CAB7692
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | IRF1 Rabbit Polyclonal Antibody |
SKU: | CAB7692 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 181-280 of human IRF1 (NP_002189.1). |
Sequence: | PALS PCAV SSTL PDWH IPVE VVPD STSD LYNF QVSP MPST SEAT TDED EEGK LPED IMKL LEQS EWQP TNVD GKGY LLNE PGVQ PTSV YGDF SCKE EPEI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | MAR; IRF-1; IRF1 |
Positive Sample: | Rat spleen,C2C12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 37kDa |
Observed MW: | 48kDa |
The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer.
Purification Method: | Affinity purification |
Gene ID: | 3659 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |