The IL-22 Polyclonal Antibody (CAB23665) is a powerful tool for researching Interleukin-22 (IL-22), a cytokine involved in inflammatory responses and tissue regeneration. This antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting IL-22 in human samples, making it a valuable asset for studies in immunology and several disease conditions.IL-22 is a key player in the regulation of tissue homeostasis and inflammation, impacting various physiological processes such as cell proliferation, survival, and barrier integrity.
Its dysregulation has been linked to autoimmune diseases, inflammatory disorders, and tissue damage, highlighting its potential as a therapeutic target.With its proven efficacy in Western blot applications, the IL-22 Polyclonal Antibody enables precise detection and analysis of IL-22 protein levels in different cell types and experimental settings. By unraveling the intricate roles of IL-22 in health and disease, researchers can pave the way for innovative treatment strategies and personalized medicine approaches.
Product Name:
IL22 Polyclonal Antibody
SKU:
CAB23665
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant protein of mouse IL22.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
IL-22; If2b1; Iltif; IL-22a; ILTIFa; IL22
Positive Sample:
Raji,Mouse thymus,CHO-IL22
Conjugate:
Unconjugated
Calculated MW:
20kDa
Observed MW:
16kDa/18kDa
Predicted to enable cytokine activity. Acts upstream of or within several processes, including negative regulation of inflammatory response; reactive oxygen species metabolic process; and regulation of tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Is expressed in retina and skin. Used to study liposarcoma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22).
Purification Method:
Affinity purification
Gene ID:
50929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IL22 Rabbit pAb (CAB23665) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
