The CD121A Polyclonal Antibody is a powerful tool for research involving the CD121A protein, a key regulator of immune responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to CD121A, researchers can easily detect and analyze this important protein in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CD121A, also known as the IL-1 receptor type I, plays a crucial role in the inflammatory response and is involved in various immune-related processes.
Its ability to interact with the cytokine IL-1 makes it an attractive target for studying diseases such as autoimmune disorders, chronic inflammation, and cancer. By gaining a deeper understanding of CD121A's function, researchers can potentially develop new therapies that modulate immune responses and improve patient outcomes in these conditions.
Product Name:
CD121a Polyclonal Antibody
SKU:
CAB22540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-332 of human CD121a. (NP_000868.1?).
external side of plasma membrane, extracellular region, plasma membrane
Calculated MW:
65kDa
Observed MW:
90kDa
This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12.
Purification Method:
Affinity purification
Gene ID:
3554
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD121a antibody (CAB22540) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
