IgM Monoclonal Antibody (CPAB0611)
- SKU:
- CPAB0611
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
Description
IgM Monoclonal Antibody (CPAB0611)
The IgM Antibody (CPAB0611) offered by AssayGenie is a high-quality research tool designed for studying IgM, an essential component of the immune system involved in the primary response to infections. This polyclonal antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for various applications, including Western blotting.IgM is the first antibody produced by the immune system in response to an infection, playing a crucial role in the activation of the complement system and the neutralization of pathogens.
Research into IgM can provide valuable insights into immune responses and potential therapeutic targets for infectious diseases and autoimmune disorders.With its specificity and reliability, the IgM Antibody (CPAB0611) from AssayGenie is a valuable tool for researchers studying the functions and mechanisms of IgM in the immune system. Its use in immunoassays and immunohistochemistry can aid in the understanding of immune responses and the development of novel approaches for diagnosing and treating immune-related conditions.
Product Name: | IgM Antibody |
Product Sku: | CPAB0611 |
Size: | 100μg |
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Immunogen: | |
Clone: | |
Reactivity: | Other bodies |
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Purification Method: | IgM antibody was purified from mouse ascitic fluids by Protein-A chromatography. |
Isotype: | |
Background: | Immunoglobulin M (IgM) is a basic antibody produced by B cells. IgM is the first antibody to emerge in response to initial exposure to an antigen. IgM antibodies are found in the blood and lymph fluid and are the third most widespread serum Ig. Immunoglobulin M (IgM), being the 3rd most widespread serum Ig and exists in two forms- mostly as a pentamer (970kDa) but also as a hexamer. The pentameric IgM has 10 binding sites since each monomer has two antigen binding sites. Due to distance constraints in the hexameric complex, the J chain is found in pentameric IgM but not in the hexameric form. IgM antibodies, which appear early in the course of an infection, typically reappear to a smaller extent after additional exposure. IgM, as opposed to IgG antibodies, do not pass across the human placenta. These properties of IgM make it suitable for the diagnosis of infectious diseases. |
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Storage Buffer: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |