The IGF2 Polyclonal Antibody (CAB2086) is a valuable tool for researchers studying insulin-like growth factor 2 (IGF2), a protein involved in cell growth and development. This polyclonal antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for a variety of research applications.IGF2 is known to play a key role in both normal growth and development, as well as in diseases such as cancer. By targeting IGF2 with this antibody, researchers can detect and analyze the protein in various cell types, providing valuable insights into its function and potential therapeutic applications.
With its validated use in Western blot applications, the IGF2 Polyclonal Antibody is a reliable tool for studies in developmental biology, cancer research, and other fields where understanding IGF2 expression and activity is critical. Researchers can trust this antibody to deliver accurate and reproducible results, helping to advance our understanding of IGF2 and its implications in health and disease.
Product Name:
IGF2 Rabbit Polyclonal Antibody
SKU:
CAB2086
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human IGF2 (NP_000603.1).
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3481
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using IGF2 Rabbit pAb (CAB2086) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
