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Human Ryanodine receptor 1 / RYR1 ELISA Kit

SKU:
HUFI01314
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P21817
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
RYR1, Ryanodine receptor 1, RYR-1, RyR1, Type 1 ryanodine receptor, Skeletal muscle-type ryanodine receptor, Skeletal muscle calcium release channel
Reactivity:
Human
Research Area:
Cell Biology
€599
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Description

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Human Ryanodine receptor 1 / RYR1 ELISA Kit

Ryanodinereceptor1/RYR1 is present in skeletal muscle and serves as a calcium release channel in the sarcoplasmic reticulum as well as a link between the sarcoplasmic reticulum and the transverse tubule. Mutations in Ryanodinereceptor1/RYR1 are linked to malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Cell-type Dependent Selectivity of CCK2R Signaling and Ion Channel Transport are two pathways associated with Ryanodinereceptor1/RYR1.