Human IgG4/Immunoglobulin heavy constant gamma 4 Polyclonal Antibody (CAB24655)
- SKU:
- CAB24655
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Human IgG4/Immunoglobulin heavy constant gamma 4 Polyclonal Antibody |
SKU: | CAB24655 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG4/Immunoglobulin heavy constant gamma 4 (P01861). |
Sequence: | VHTF PAVL QSSG LYSL SSVV TVPS SSLG TKTY TCNV DHKP SNTK VDKR VESK YGPP CPSC PAPE FLGG PSVF LFPP KPKD TLMI SRTP EVTC VVVD VSQE D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IGHG4; Ig gamma-4 chain C region; Human IgG4/Immunoglobulin heavy constant gamma 4 |
Positive Sample: | RPMI-8226,SH-SY5Y,Daudi,U-251 MG,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted |
Calculated MW: | 44kDa |
Observed MW: | 36kDa |
Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |