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GenieFluor 647 Anti-Human CD62L Antibody [DREG56] (AGEL0955)

SKU:
AGEL0955
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$167 - $563
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD62L Antibody [DREG56]

The Human CD62L Monoclonal Antibody (AF647 Conjugated) - DREG56 (AGEL0955) is a cutting-edge tool for immunological research involving CD62L, a critical cell surface marker involved in immune cell trafficking and activation. This antibody, with its AF647 conjugation for fluorescent detection, specifically targets human CD62L, enabling precise visualization and quantification in various experimental settings.CD62L, also known as L-selectin, plays a pivotal role in the recruitment of immune cells to sites of inflammation and lymphoid organs. By facilitating the interaction between circulating leukocytes and endothelial cells, CD62L is essential for the initiation of immune responses and the maintenance of immune surveillance.

Its dynamic expression pattern and functional significance in immune cell migration make it a key molecule of interest in studies related to immune system function and dysfunction.By utilizing the Human CD62L Monoclonal Antibody (AF647 Conjugated) - DREG56 (AGEL0955), researchers can delve into the intricate mechanisms underlying immune cell trafficking and homeostasis. From investigating immune cell activation to studying the impact of inflammatory diseases on CD62L expression, this antibody provides a powerful tool for elucidating the role of CD62L in health and disease. Trust in its reliability, specificity, and versatility for advancing your immunological research endeavors.

Product Title:GenieFluor 647 Anti-Human CD62L Antibody [DREG56]
SKU:AGEL0955
Size:20 Tests, 100 Tests, 200 Tests
Clone No:DREG56
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14151
Gene ID:6402
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

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