The Human CD5 Monoclonal Antibody FITC Conjugated (UCHT2) AGEL0188 is a specialized tool for researchers studying CD5, a cell surface glycoprotein widely expressed on T cells. This antibody, originating from mouse monoclonal sources, is adept at binding to human samples and is optimized for flow cytometry applications, particularly for the detection and analysis of CD5-expressing cells in various biological samples.CD5, a marker associated with T cell activation and signaling pathways, is a key player in immune responses and tolerance mechanisms. Its presence on the surface of T cells enables intricate interactions within the immune system, aiding in both activation and suppression of immune responses as needed.
CD5's involvement in regulating T cell functions makes it a focal point in research related to immunology, autoimmunity, and infectious diseases.Utilizing the Human CD5 Monoclonal Antibody FITC Conjugated (UCHT2) AGEL0188 provides researchers with a precise tool to investigate the role of CD5 in immune responses and T cell activities. By accurately detecting and quantifying CD5-expressing cells, this antibody facilitates detailed studies that can lead to a better understanding of immune responses in different physiological and pathological conditions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06127
Gene ID:
921
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.