The Human CD38 Monoclonal Antibody PE-Cyanine5.5 Conjugated (HIT2) (AGEL0991) is a powerful tool for researchers studying CD38, a cell surface molecule involved in immune response and various biological processes. This antibody, produced through advanced manufacturing processes, is highly specific and sensitive for human samples, and is ideal for use in flow cytometry and fluorescence microscopy applications.CD38, a multifunctional protein found on immune cells, is known for its role in immune regulation and cell signaling. It is implicated in a wide range of physiological processes, including inflammation, cell adhesion, and cell differentiation.
Studies have shown that aberrant expression of CD38 is associated with various diseases, making it an interesting target for therapeutic intervention.By using the Human CD38 Monoclonal Antibody PE-Cyanine5.5 Conjugated (HIT2) (AGEL0991), researchers can accurately detect and quantify CD38 expression in different cell types, aiding in the understanding of its function and potential therapeutic implications. This antibody is a valuable tool for investigations in immunology, cancer research, and autoimmune disorders, helping researchers unravel the complexities of CD38 biology and its impact on human health.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.