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GenieFluor 647 Anti-Human CD32 Antibody [IV-3] (AGEL1078)

SKU:
AGEL1078
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$251 - $755
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD32 Antibody [IV-3]

The Human CD32 Monoclonal Antibody (AF647 Conjugated) IV.3 (AGEL1078) is a cutting-edge tool designed for research involving CD32, a cell surface receptor known for its role in immune cell function and regulation. This antibody, derived from hybridoma cells, offers high specificity and sensitivity for detecting CD32 in human samples. It is validated for use in various experimental techniques such as flow cytometry and immunofluorescence, enabling precise identification and analysis of CD32-expressing cells in diverse research applications.CD32, also known as Fc gamma receptor II, is a crucial component of the immune system, mediating immune responses by binding to immune complexes and regulating immune cell activation. Its intricate function in immune signaling pathways makes it a key target for investigations related to immunology, infectious diseases, and autoimmune disorders.

By elucidating the role of CD32 in immune regulation, researchers can gain insights into mechanisms underlying immune-mediated conditions and develop targeted therapeutic strategies to modulate immune responses effectively.The Human CD32 Monoclonal Antibody (AF647 Conjugated) IV.3 (AGEL1078) provides a valuable tool for researchers seeking to unravel the complexities of CD32 biology and its implications in health and disease. With its exceptional performance and specificity, this antibody is an essential resource for advancing our understanding of immune responses and developing innovative approaches for therapeutic interventions.

Product Title:GenieFluor 647 Anti-Human CD32 Antibody [IV-3]
SKU:AGEL1078
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IV-3
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor 647 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P31994
Gene ID:2212
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

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