The Human CD29 Monoclonal Antibody (Biotin Conjugated, TS2/16, 2.1) from Assay Genie (AGEL0213) is a powerful tool for researchers studying CD29, a key cell surface adhesion molecule with diverse functions in cell migration, differentiation, and signaling. This antibody, created with high specificity and sensitivity, is suitable for various applications such as flow cytometry, immunohistochemistry, and immunoprecipitation.CD29, also known as integrin beta-1, plays a crucial role in cell adhesion and communication within the extracellular matrix, influencing processes like cell proliferation, migration, and survival. The versatility of this antibody allows for the detection and analysis of CD29 expression in different cell types and tissues, making it ideal for investigations in developmental biology, cancer research, and regenerative medicine.
With its ability to specifically target CD29, researchers can gain valuable insights into the molecular mechanisms underlying cell adhesion and migration, paving the way for potential therapeutic interventions in conditions related to abnormal cell behavior. Invest in the Human CD29 Monoclonal Antibody from Assay Genie to advance your research and uncover new discoveries in cell biology and disease pathogenesis.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.