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PE Anti-Human CD200 Antibody [OX-104] (AGEL1811)

SKU:
AGEL1811
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$227 - $755
Frequently bought together:

Description

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PE Anti-Human CD200 Antibody [OX-104]

The Human CD200 Monoclonal Antibody (PE Conjugated) - Ox-104 (AGEL1811) is a cutting-edge tool designed for researchers studying CD200, a cell surface glycoprotein with immunomodulatory properties. This monoclonal antibody, conjugated with PE for fluorescent detection, is specifically engineered to target human CD200 molecules, enabling precise identification and analysis in a variety of cell types.CD200 is recognized for its role in immune regulation and tolerance induction, making it a key player in maintaining immune balance and preventing excessive immune responses. Research on CD200 has implications in various fields including immunology, neurology, and oncology. Given its ability to suppress inflammatory responses and promote immune tolerance, understanding CD200's function is crucial for advancing therapies targeting autoimmune diseases, transplant rejection, and inflammatory conditions.

This meticulously validated monoclonal antibody, Ox-104 (AGEL1811), provides researchers with a reliable tool for studying CD200 expression and function in human samples, facilitating investigations into immune signaling pathways and potential therapeutic strategies. Expanding knowledge on CD200 through the use of this antibody can open up new avenues for exploring immune modulation mechanisms and developing novel treatments for a range of diseases.

Product Title:PE Anti-Human CD200 Antibody [OX-104]
SKU:AGEL1811
Size:20 Tests, 100 Tests, 200 Tests
Clone No:OX-104
Synonyms:MOX1;MOX2;My033;CD 200;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P41217
Gene ID:4345
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD200, also known as OX2, is a member of the immunoglobulin superfamily (IgSF). It is a monomorphic cell surface glycoprotein that is expressed on thymocytes, neurons, endothelium, follicular dendritic cells in all lymphoid organs, a subset of CD34+ progenitor cells, and at low levels on some smooth muscle and B lymphocytes. It is not expressed on NK cells, monocytes, granulocytes, or platelets. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. The interaction between CD200 (OX2) and CD200 receptor (OX2R) system is of importance in the control of macrophage and granulocyte activation, which may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.

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