The Human AGER Polyclonal Antibody is a specialized antibody designed for research involving AGER, a cell surface receptor involved in cellular stress response and inflammation regulation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it a valuable tool for studies in immunology, inflammation, and cancer research.AGER, also known as receptor for advanced glycation end products, is a key player in the pathogenesis of various diseases, including diabetes, neurodegenerative disorders, and inflammatory conditions.
By targeting AGER with this polyclonal antibody, researchers can better understand its role in disease progression and potentially develop new therapeutic strategies.Validated for use in Western blot applications, the Human AGER Polyclonal Antibody binds specifically to the AGER protein, allowing for precise detection and analysis in various cell types. Its reliability and specificity make it an essential tool for scientists studying the molecular mechanisms underlying disease processes and inflammation.
Product Name:
Human AGER Polyclonal Antibody
SKU:
CAB22536
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-344 of human AGER(NP_001127.1).
The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847).
Purification Method:
Affinity purification
Gene ID:
177
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung using Human AGER Rabbit pAb(CAB22536) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time:0.1s.
