The HOXB1, HOXA1, and HOXD1 Polyclonal Antibody (PAC021732) is a valuable tool for researchers studying the HOX family of transcription factors, which play essential roles in cellular processes such as development, differentiation, and proliferation. This antibody, produced in rabbits, is highly specific for detecting HOXB1, HOXA1, and HOXD1 proteins in human samples and has been validated for use in Western blot applications.HOX genes are known for their role in embryonic development and have been implicated in various diseases, including cancer. The HOXB1, HOXA1, and HOXD1 Polyclonal Antibody enables researchers to investigate the expression levels and localization of these specific HOX proteins in different cell types, providing valuable insights into their functions and potential therapeutic implications.
By utilizing this antibody in their research, scientists can deepen their understanding of HOXB1, HOXA1, and HOXD1 and their contributions to normal development and disease progression. This antibody is a powerful tool for studies in developmental biology, cancer biology, and regenerative medicine.
Antibody Name:
HOXB1/HOXA1/HOXD1 Antibody (PACO21732)
Antibody SKU:
PACO21732
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human HOXA1/B1/D1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Piper D.E., Cell 96:587-597(1999).
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human testis tissue, using HOXA1/B1/D1 antibody.
Synonyms:
Homeobox protein Hox-B1; Hox-2I; HOXB1; HOX2I;
UniProt Protein Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
NCBI Summary:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008]
