The HMGCS1 Polyclonal Antibody (PAC037766) is a vital tool for researchers studying the HMGCS1 protein, an enzyme involved in ketogenesis and cholesterol biosynthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the HMGCS1 protein, this antibody enables precise detection and analysis in various cell types, making it well-suited for investigations in metabolism, lipid biology, and related fields.HMGCS1 plays a crucial role in metabolic processes, including the production of ketone bodies during fasting and the synthesis of cholesterol in cells. Dysregulation of HMGCS1 has been linked to metabolic disorders such as hypercholesterolemia and certain types of cancer.
By studying the function and regulation of HMGCS1, researchers can gain valuable insights into metabolic pathways and potential therapeutic targets for metabolic diseases.Overall, the HMGCS1 Polyclonal Antibody is an essential tool for researchers interested in unraveling the complex roles of the HMGCS1 enzyme in metabolism and disease. Its high specificity and sensitivity make it a reliable choice for various experimental approaches, providing valuable data for advancing our understanding of metabolic pathways and their implications for human health.
Antibody Name:
Hmgcs1 Antibody (PACO37766)
Antibody SKU:
PACO37766
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein (1-520AA)
Western blot. All lanes: Hmgcs1 antibody at 12µg/ml. Lane 1: NIH/3T3 whole cell lysate. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 58 kDa. Observed band size: 58 kDa.
Background:
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
