The HMBOX1 Polyclonal Antibody (PACO09740) is a vital tool for researchers studying HMBOX1, a protein involved in gene regulation and cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards HMBOX1 in human samples, making it suitable for use in Western blot applications. By binding to HMBOX1, this antibody enables precise detection and analysis in various cell types, making it a valuable asset for studies in genetics, molecular biology, and cancer research.
HMBOX1 is a key player in regulating gene expression and cellular functions, with implications in various biological processes such as cell growth, proliferation, and differentiation. Understanding the role of HMBOX1 is essential for deciphering its involvement in diseases like cancer, genetic disorders, and developmental abnormalities. Targeting HMBOX1 holds promise in developing strategies for diagnosing and treating conditions influenced by its dysregulation.
HMBOX1: Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulation; DNA-bindingChromosomal Location of Human Ortholog: 8p21.1Cellular Component: cytoplasm; nuclear chromosome, telomeric region; nucleus; telomerase holoenzyme complexMolecular Function: double-stranded telomeric DNA binding; protein binding; protein complex binding; telomerase activity; telomeric DNA bindingBiological Process: negative regulation of transcription, DNA-dependent; positive regulation of telomerase activity; positive regulation of telomere maintenance via telomerase
