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HAX1 Monoclonal Antibody [PAT3C5AT] (CPAB0567)

SKU:
CPAB0567
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT3C5AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

HAX1 Monoclonal Antibody [PAT3C5AT] (CPAB0567)

The HAX1 Polyclonal Antibody (CPAB0567) is a valuable tool for researchers studying the HAX1 protein, which plays a crucial role in various cellular processes including immune responses and apoptosis. This antibody, derived from rabbits, is specifically designed for use in Western blotting applications and is highly reactive with human samples.HAX1 is a multifunctional protein that is involved in regulating mitochondrial function, cell survival, and immune cell development. Dysregulation of HAX1 has been linked to diseases such as severe congenital neutropenia and certain types of cancer, making it an important target for research.

With the HAX1 Polyclonal Antibody, researchers can accurately detect and analyze the expression of HAX1 in a variety of cell types, providing valuable insights into its role in health and disease. This antibody is a valuable tool for studies in immunology, oncology, and other fields that rely on understanding the intricate mechanisms of cellular function.

Product Name:HAX1 Antibody
Product Sku:CPAB0567
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HAX1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HAX1 amino acids 1-279 purified from Ecoli.
Clone:PAT3C5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:HAX1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:HAX1 associates with hematopoietic cell-specific Lyn substrate 1, which is a substrate of Src family tyrosine kinases. HAX1 also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought HAX1 is mainly localized to the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in the HAX1 gene result in autosomal recessive severe congenital neutropenia, aka Kostmann disease.
Synonyms:HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HAX-1, HSP1BP-1, HAX1, HS1BP1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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