The GRIP1 Polyclonal Antibody (CAB16503) is a valuable tool for researchers studying GRIP1, a protein involved in the regulation of synaptic transmission and plasticity in the brain. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the GRIP1 protein, this antibody allows for the detection and analysis of GRIP1 levels in various cell types, making it ideal for studies in neuroscience and neurobiology.GRIP1, also known as glutamate receptor-interacting protein 1, is crucial for the proper functioning of glutamatergic synapses and the modulation of synaptic strength.
Dysregulation of GRIP1 has been implicated in neurological disorders such as schizophrenia, Alzheimer's disease, and epilepsy. By investigating the role of GRIP1 in these conditions, researchers can gain insights into the underlying mechanisms and potentially develop new therapeutic strategies.Overall, the GRIP1 Polyclonal Antibody is a valuable tool for researchers seeking to better understand the role of GRIP1 in synaptic function and neurological disorders. Its high specificity and reliability make it an essential component for studies aimed at uncovering the complex mechanisms that govern synaptic transmission in the brain.
Product Name:
GRIP1 Rabbit Polyclonal Antibody
SKU:
CAB16503
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human GRIP1 (NP_001171545.1).
This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
23426
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using GRIP1 Rabbit pAb (CAB16503) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
