The GPR151 Polyclonal Antibody (CAB16165) is specifically designed for research involving GPR151, a G protein-coupled receptor implicated in various physiological processes. This rabbit-raised antibody is highly reactive with human samples and has been validated for Western blot applications, allowing for efficient detection and analysis of the GPR151 protein in different cell types.GPR151 is known to play a crucial role in the central nervous system, particularly in neurotransmission and neuroendocrine regulation. Its involvement in these processes makes it a promising target for research in neuroscience, drug development, and neurodegenerative disorders.
By understanding the function and activity of GPR151, researchers can gain insights into its potential therapeutic implications in various neurological conditions.By utilizing the GPR151 Polyclonal Antibody, scientists can further explore the role of GPR151 in the context of brain function and pathology. This antibody enables the precise detection and quantification of GPR151 protein levels, providing valuable information for studies focused on understanding the molecular mechanisms underlying neurological disorders and developing targeted treatments.
Product Name:
GPR151 Rabbit Polyclonal Antibody
SKU:
CAB16165
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-419 of human GPR151 (NP_919227.2).
This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the SOG subfamily that includes somatostatin, opioid, galanin, and kisspeptin receptors. The orthologous mouse gene has a restricted pattern of neuronal expression which is induced following nerve injury. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes.
Purification Method:
Affinity purification
Gene ID:
134391
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPR151 Rabbit pAb (CAB16165) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
