The GP9 Polyclonal Antibody (CAB5374) is a valuable tool for researchers studying the GP9 protein, which plays a crucial role in platelet activation and aggregation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding specifically to the GP9 protein, this antibody enables accurate detection and analysis of GP9 in various cell types, making it ideal for studies in hematology and cardiovascular research. Understanding the function of GP9 is essential for unraveling the mechanisms underlying platelet activation and thrombus formation, providing insights that could lead to the development of novel therapeutic strategies for various cardiovascular conditions.
Overall, the GP9 Polyclonal Antibody is a valuable resource for scientists seeking to deepen their understanding of platelet biology and the role of GP9 in hemostasis and cardiovascular health. Its versatility and reliability make it a valuable asset for research endeavors seeking to uncover new insights into the complexities of platelet function and thrombotic disorders.
Product Name:
GP9 Rabbit Polyclonal Antibody
SKU:
CAB5374
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 17-147 of human GP9 (NP_000165.1).
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Purification Method:
Affinity purification
Gene ID:
2815
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using GP9 Rabbit pAb (CAB5374) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
