The GNG4 Polyclonal Antibody (PAC027085) is a valuable tool for researchers studying GNG4, a protein involved in G protein signaling pathways. The antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the GNG4 protein, allowing for accurate detection and analysis in various cell types.GNG4 is a member of the G protein family, playing a crucial role in signal transduction and cell communication. Dysregulation of G protein signaling pathways has been linked to various diseases, including cancer, cardiovascular disorders, and neurological conditions.
Therefore, understanding the function of GNG4 is essential for advancing research in these fields.By using the GNG4 Polyclonal Antibody, researchers can gain insights into the role of GNG4 in cellular processes and disease development. This antibody is a valuable tool for investigating G protein signaling pathways and exploring potential therapeutic targets for a wide range of health conditions.
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO27085 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO27085 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO27085 at dilution of 1:100.
Background:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The β and γ chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Synonyms:
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4, GNG4, GNGT4
