The GLP2R Polyclonal Antibody (CAB6602) is a valuable tool for researchers studying the GLP2R protein, a G-protein coupled receptor involved in regulating various physiological processes, including energy metabolism and gastrointestinal functions. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. By binding to the GLP2R protein, researchers can effectively detect and analyze its expression in different cell types, making it suitable for investigations in the fields of metabolism, nutrition, and gastrointestinal disorders.
The GLP2R receptor, known as a key player in maintaining energy balance and regulating intestinal functions, presents promising therapeutic opportunities for addressing metabolic disorders and gastrointestinal conditions. Understanding the role of GLP2R in metabolic pathways and gut health is essential for developing innovative treatments for conditions such as obesity, diabetes, and gastrointestinal diseases. The GLP2R Polyclonal Antibody serves as a valuable tool in unraveling the complex mechanisms involving this receptor, paving the way for advancements in biomedical research and drug development.
Product Name:
GLP2R Rabbit Polyclonal Antibody
SKU:
CAB6602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R (NP_004237.1).
This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
Purification Method:
Affinity purification
Gene ID:
9340
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using GLP2R Rabbit pAb (CAB6602) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.