The GLIPR1 Polyclonal Antibody (CAB16490) is a powerful tool for researchers investigating the GLIPR1 protein, which is involved in regulating cell growth and apoptosis. This antibody, produced in rabbits, shows high specificity and sensitivity in detecting GLIPR1 in human samples, making it a valuable asset for studies in cancer and cell biology.GLIPR1, also known as glioma pathogenesis-related protein 1, has been linked to the progression of various cancers and is being explored as a potential therapeutic target. By targeting GLIPR1, researchers aim to better understand its role in tumorigenesis and ultimately develop novel treatments for cancer patients.
With its proven efficacy in Western blot applications, this polyclonal antibody enables accurate detection and analysis of GLIPR1 expression in different cell types, providing valuable insights into its function and potential as a diagnostic or therapeutic target. Researchers in oncology and molecular biology will find this antibody indispensable for their studies on GLIPR1 and its impact on cancer biology.
Product Name:
GLIPR1 Rabbit Polyclonal Antibody
SKU:
CAB16490
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-140 of human GLIPR1 (NP_006842.2).
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Purification Method:
Affinity purification
Gene ID:
11010
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat lung, using GLIPR1 Rabbit pAb (CAB16490) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
