The GenieFluor Violet 450 Anti-Rat CD4 (Domain 1) Antibody (OX-38) is a crucial tool for researchers studying immune responses in rats. This monoclonal antibody, with specificity towards the CD4 antigen, offers high sensitivity and specificity for detecting CD4-positive cells in experimental settings. Its superior performance in flow cytometry and immunohistochemistry applications makes it an invaluable asset for investigations into immune cell populations and their functions.The CD4 antigen, a key marker of helper T cells, plays a central role in orchestrating immune responses by interacting with major histocompatibility complex (MHC) class II molecules. Monitoring CD4 expression levels and distribution is essential for understanding T cell activation, differentiation, and immune regulation.
The OX-38 antibody specifically targets Domain 1 of the CD4 molecule in rats, providing researchers with a precise tool for characterizing T cell subsets and studying immune-mediated processes in relevant animal models.By utilizing the GenieFluor Violet 450 Anti-Rat CD4 (Domain 1) Antibody (OX-38), researchers can delve deeper into the complexities of immune function and immune-related disorders in rat models. This cutting-edge research reagent enhances the ability to explore cellular interactions, immune responses, and therapeutic interventions, ultimately advancing our knowledge of immunology and facilitating the development of novel treatments for a variety of diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05540
Gene ID:
24932
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD4, also known as T4, is a 55kD glycoprotein member of the immunoglobin superfamily and is expressed on majority of thymocytes, macrophages, and a peripheral T cell subset (T helper cells). CD4 is a T cell co-receptor that interacts with the MHC class II molecule and is involved in T cell activation.