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GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL2947)

SKU:
AGEL2947
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
CI:A3-1
Conjugation:
AFViolet 450
€199 - €539
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1]

The GenieFluor Violet 450 Anti-Mouse F4/80 Antibody (CI:A3-1) is a highly specific tool designed for researchers studying immune cells, particularly macrophages in mouse models. This antibody, developed by Assay Genie, recognizes the F4/80 antigen, a well-known marker for mouse macrophages, making it an essential component for immunology and inflammation research.Macrophages are key players in the immune system, contributing to various physiological processes such as tissue homeostasis, immune responses, and inflammation. The F4/80 antigen, widely expressed on the surface of mature macrophages, serves as a reliable indicator for identifying and studying these important immune cells.The GenieFluor Violet 450 Anti-Mouse F4/80 Antibody (CI:A3-1) offers exceptional sensitivity and specificity in detecting F4/80-expressing macrophages, allowing for precise analysis and characterization of these cells in experimental settings.

Researchers can utilize this antibody in flow cytometry, immunofluorescence, and other immunological techniques to investigate macrophage functions, distribution, and interactions in diverse biological contexts. By using the GenieFluor Violet 450 Anti-Mouse F4/80 Antibody (CI:A3-1), researchers can deepen their understanding of macrophage biology and explore the roles of these vital immune cells in health and disease, paving the way for new insights and therapeutic strategies in immunology and related fields.

Product Title:GenieFluor Violet 450 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL2947
Size:25µg, 100µg
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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