The GenieFluorâ„¢ Violet 450 Anti-Human CD57 Antibody (HNK-1) is a cutting-edge tool for researchers studying the CD57 antigen, a marker associated with natural killer cells and a subset of T cells. This antibody, engineered for high specificity and sensitivity, boasts a violet 450 fluorescence for robust detection in flow cytometry and immunofluorescence applications.The CD57 antigen, also known as HNK-1, is a key player in immune responses and has been implicated in various diseases, including autoimmune disorders and cancer. By targeting CD57, researchers can gain valuable insights into the function and behavior of specific immune cell populations, paving the way for innovative advancements in immunotherapy and disease diagnosis.
With its advanced formulation and superior performance, the GenieFluorâ„¢ Violet 450 Anti-Human CD57 Antibody (HNK-1) is an indispensable tool for unraveling the complexities of immune cell dynamics and exploring new therapeutic strategies in the realm of immunology and oncology. Elevate your research capabilities and unlock the potential of CD57 with this state-of-the-art antibody from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
27087
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).