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GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2965)

SKU:
AGEL2965
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
M1/70
Conjugation:
AFRed 780
€179 - €409
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70]

The GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody (M1/70) is a cutting-edge tool for researchers investigating the CD11b protein, a key marker of myeloid cells involved in inflammatory responses and immune regulation. This highly specific antibody, optimized for use in flow cytometry and immunofluorescence techniques, targets the CD11b antigen present on both mouse and human cells with exceptional accuracy and sensitivity.CD11b, also known as integrin alpha M, plays a pivotal role in various cellular processes, including adhesion, migration, and phagocytosis. By targeting this integral protein, researchers can gain valuable insights into the function and behavior of myeloid cells in different biological contexts.

Furthermore, the GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody facilitates the visualization and quantification of CD11b-expressing cells, enabling detailed studies in immunology, inflammation, and disease research.With its superior performance and versatility, this advanced antibody provides researchers with a powerful tool to explore the intricate workings of the immune system and uncover novel therapeutic targets in conditions such as autoimmune diseases, infections, and cancer. Trust in the precision and reliability of the GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody to enhance your research and drive new discoveries in the field of immunology.

Product Title:GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL2965
Size:25µg, 100µg
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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