GenieFluor Red 780 Anti-Human CD8a Antibody [OKT-8]
The GenieFluor Red 780 Anti-Human CD8a Antibody (OKT-8) offered by Assay Genie is a highly specific and reliable tool for researchers investigating immune responses and cell signaling pathways. This monoclonal antibody is designed to target CD8a, a key cell surface marker found on cytotoxic T cells, and is particularly effective for flow cytometry and immunofluorescence applications.With its exceptional specificity for human CD8a, the OKT-8 antibody enables researchers to accurately identify and analyze CD8a-expressing cells in a variety of experimental settings. Whether studying immune cell populations in cancer research, immunology, or infectious diseases, this antibody provides valuable insights into the role of CD8a in immune function and pathogenesis.
The GenieFluor Red 780 Anti-Human CD8a Antibody (OKT-8) is rigorously validated for its performance and specificity, ensuring reproducible and robust results in diverse research applications. Researchers can trust this antibody to deliver accurate and consistent data, making it an essential tool for advancing our understanding of immune responses and immune cell function.
Product Title:
GenieFluor Red 780 Anti-Human CD8a Antibody [OKT-8]
Genie Fluor Red 780 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01732
Gene ID:
925
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.