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GenieFluor 647 Anti-Mouse CD150 Antibody [TC15-12F12.2] (AGEL3370)

SKU:
AGEL3370
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, λ
Clone:
TC15-12F12.2
Conjugation:
AF647
€199 - €449
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD150 Antibody [TC15-12F12.2]

The GenieFluor 647 Anti-Mouse CD150 Antibody (TC-15-12F12-2) is a powerful tool for researchers investigating the role of CD150, a cell surface marker involved in immune regulation and hematopoiesis. This antibody, optimized for use in flow cytometry and immunofluorescence applications, is specifically designed to target the mouse CD150 protein, enabling accurate and reliable detection in various experimental settings.CD150, also known as signaling lymphocytic activation molecule family member 1 (SLAMF1), is a key player in regulating immune cell activation and differentiation, making it a crucial molecule for studying immune responses and immune cell interactions. The GenieFluor 647 Anti-Mouse CD150 Antibody provides researchers with a valuable tool to analyze the expression and function of CD150 in different cell populations, aiding in the understanding of immune system dynamics and immune-mediated diseases.

With its high specificity and sensitivity, this antibody is a valuable reagent for immunology research, particularly in the fields of immunotherapy, infectious diseases, and hematopoiesis. By targeting CD150, researchers can gain insights into the complex mechanisms underlying immune responses and potentially develop novel therapeutic strategies targeting this important immune regulator. The GenieFluor 647 Anti-Mouse CD150 Antibody is a reliable reagent that empowers researchers to delve deeper into the intricate workings of the immune system and pave the way for innovative discoveries in immunology.

Product Title:GenieFluor 647 Anti-Mouse CD150 Antibody [TC15-12F12.2]
SKU:AGEL3370
Size:50 Tests, 100 Tests, 200 Tests
Clone No:TC15-12F12.2
Synonyms:Slam;Slamf1;CD 150;Signaling lymphocytic activation molecule;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, λ
Isotype Control:Genie Fluor 647 Rat IgG2a, λ Isotype Control[B39-4]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q9QUM4
Gene ID:27218
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

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