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GenieFluor 647 Anti-Human CD28 Antibody [CD28.2] (AGEL2374)

SKU:
AGEL2374
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
CD28.2
Conjugation:
AF647
€189 - €709
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD28 Antibody [CD28.2]

The GenieFluor 647 Anti-Human CD28 Antibody (CD28-2) from AssayGenie is an essential tool for researchers investigating the CD28 protein, a key regulator of T cell activation and immune response. This monoclonal antibody is specifically designed for use with human samples and is validated for various applications including flow cytometry and immunofluorescence.CD28 is a critical co-stimulatory molecule expressed on T cells that provides essential signals for T cell activation and proliferation.

By targeting CD28, researchers can gain valuable insights into immune system function, immune disorders, and potential therapeutic targets for modulating immune responses.With its high specificity and sensitivity, the GenieFluor 647 Anti-Human CD28 Antibody (CD28-2) offers researchers a reliable tool for studying the role of CD28 in immune response modulation, autoimmune diseases, and cancer immunotherapy. Unlock the potential of your research with this advanced antibody from AssayGenie.

Product Title:GenieFluor 647 Anti-Human CD28 Antibody [CD28.2]
SKU:AGEL2374
Size:20 Tests, 100 Tests, 200 Tests
Clone No:CD28.2
Synonyms:PAS2;MNS;HGpMiX;GYPA;GPSAT;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10747
Gene ID:940
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

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