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GenieFluor 488 Anti-Human CD20 Antibody [2H7] (AGEL2399)

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SKU AGEL2399
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone 2H7
Conjugation AF488
€100 - €428
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Description

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GenieFluor 488 Anti-Human CD20 Antibody [2H7]

The GenieFluor 488 Anti-Human CD20 Antibody (2H7) offered by AssayGenie is a cutting-edge research tool designed for studying CD20, a cell surface antigen predominantly expressed on B cells. This antibody, specifically engineered for human samples, provides high sensitivity and specificity in various immunofluorescence applications.CD20 is a crucial marker in B cell biology and is commonly targeted in therapies for B cell-related disorders such as lymphomas and leukemias. The GenieFluor 488 Anti-Human CD20 Antibody (2H7) facilitates the visualization and analysis of CD20 expression, making it an indispensable tool for investigating B cell biology, immune responses, and potential therapeutic strategies.

With its superior performance and reliability, this antibody opens up new possibilities for researchers in the fields of immunology, oncology, and autoimmune diseases. Trust AssayGenie's GenieFluor 488 Anti-Human CD20 Antibody (2H7) to accelerate your research and unlock the mysteries of CD20 biology.

Product Title:GenieFluor 488 Anti-Human CD20 Antibody [2H7]
SKU:AGEL2399
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Genie Fluor 488 Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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