Description
FXYD7 Antibody (CAB14895)
The FXYD7 Antibody (CAB14895) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the FXYD7 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for research in physiology and disease mechanisms.FXYD7, a member of the FXYD family of ion transport regulators, is known to modulate the activity of Na+/K+-ATPase pumps, which are crucial for maintaining ion gradients across cell membranes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
| Product Name: | FXYD7 Antibody |
| SKU: | CAB14895 |
| Size: | 20μL, 100μL |
| Reactivity: | Mouse, Rat |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | MATP TQTP TKAP EEPD PFYY DYNT VQTV GMTL ATIL FLLG ILIV ISKK VKCR KADS RSES PTCK SCKS ELPS SAPG GGGV | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | FXYD7 |
| Positive Sample: | Mouse brain, Rat brain |
| Cellular Localization: | Membrane, Single-Pass Membrane Protein. |
| Calculated MW: | 9kDa |
| Observed MW: | 18kDa |
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Dec 2000]
| Purification Method | Affinity purification |
| Gene ID | 53822 |
| RRID | AB_2761776 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using FXYD7 Rabbit pAb (CAB14895) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s. |
