The FRAT1 Monoclonal Antibody is a cutting-edge tool for researchers studying FRAT1, a key player in the Wnt signaling pathway. This antibody, produced using advanced monoclonal technology, offers high specificity and sensitivity for detecting FRAT1 in a variety of samples. Validated for use in various applications, including immunohistochemistry and flow cytometry, this antibody allows for precise analysis of FRAT1 expression in different cell types and tissues.FRAT1 is a crucial regulator of Wnt signaling, a pathway involved in cell proliferation, differentiation, and development.
Dysregulation of this pathway has been implicated in various diseases, including cancer and developmental disorders. By targeting FRAT1, researchers can gain insights into the mechanisms underlying Wnt signaling and its impact on disease progression. This antibody provides a valuable tool for exploring the role of FRAT1 in both normal physiology and pathological conditions, paving the way for the development of novel therapeutic strategies targeting the Wnt pathway.
Product Name:
FRAT1 Monoclonal Antibody
SKU:
CAB21071
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-170 of human FRAT1 (NP_005470.2).
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
Purification Method:
Affinity purification
Gene ID:
10023
Clone Number:
ARC2842
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using FRAT1 Rabbit mAb (CAB21071) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
