The FPR3 Antibody (PACO03723) is a polyclonal antibody designed for research involving the Formyl peptide receptor 3 (FPR3) protein. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for studies in immunology and inflammation research. FPR3 is a cell surface receptor that plays a crucial role in the activation of neutrophils and other immune cells in response to bacterial infections. It is involved in chemotaxis and the regulation of inflammatory responses. The FPR3 Antibody enables detection and analysis of the FPR3 protein in various cell types, providing valuable insights into its function in immune regulation.
Understanding the role of FPR3 in the immune response is essential for developing novel therapies targeting inflammatory conditions, infectious diseases, and autoimmune disorders. The FPR3 Antibody offers researchers a high-quality tool for investigating the function and regulation of FPR3, advancing our knowledge of immune signaling pathways and potential therapeutic targets.
Antibody Name:
FPR3 Antibody
Antibody SKU:
PACO03723
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human FPRL2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
FPR3: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: plasma membraneBiological Process: cell motility; signal transduction
