The Foxred2 Polyclonal Antibody (PACO52534) is a valuable tool for research involving the Foxred2 protein, which is involved in mitochondrial function and redox regulation. This antibody, produced in rabbits, is highly specific to Foxred2 and has been validated for use in various applications such as Western blot and immunofluorescence.Foxred2 is an important player in maintaining the integrity and function of mitochondria, the powerhouse of the cell. Dysregulation of Foxred2 has been linked to various diseases, including neurodegenerative disorders and cancer.
By using the Foxred2 Polyclonal Antibody, researchers can study the expression and localization of Foxred2 in different cell types and tissues, shedding light on its role in health and disease.Overall, the Foxred2 Polyclonal Antibody is a reliable tool for investigating the function of Foxred2 in mitochondrial biology and its implications in physiological and pathological conditions. Its high specificity and sensitivity make it an essential reagent for studies in cell biology, biochemistry, and disease mechanisms involving mitochondrial dysfunction.
Antibody Name:
FOXRED2 Antibody (PACO52534)
Antibody SKU:
PACO52534
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human FAD-dependent oxidoreductase domain-containing protein 2 protein (501-684AA)
Immunohistochemistry of paraffin-embedded human brain tissue using PACO52534 at dilution of 1:100.
Background:
Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation.
Synonyms:
FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation), FOXRED2, ERFAD
UniProt Protein Function:
FOXRED2: Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Belongs to the FOXRED2 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 22q12.3Cellular Component: endoplasmic reticulum lumenMolecular Function: protein binding; FAD binding; oxidoreductase activity; glycoprotein bindingBiological Process: ER-associated protein catabolic process
