The FOXO6 Polyclonal Antibody (PAC062899) is a valuable tool for researchers studying the FOXO6 protein, a member of the FOXO family of transcription factors known for their role in regulating cellular processes such as apoptosis, cell cycle control, and metabolism. This antibody, produced in rabbits, demonstrates high specificity in detecting FOXO6 in human samples and has been validated for use in Western blot applications.FOXO6 is particularly interesting in the fields of neuroscience and aging research, as it plays a key role in neuronal survival, synaptic plasticity, and age-related cognitive decline.
By targeting FOXO6, researchers can gain insights into the molecular mechanisms underlying these processes and potentially identify therapeutic targets for neurological disorders and age-related cognitive impairments.With its high reactivity and specificity, the FOXO6 Polyclonal Antibody is an essential tool for researchers interested in unraveling the functions of FOXO6 in various biological contexts, making it an ideal choice for studies in neurobiology, aging, and neurodegenerative diseases.
IHC image of PACO62899 diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells with PACO62899 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
