The FGF2 Monoclonal Antibody (CAB22448) is a valuable tool for research involving Fibroblast Growth Factor 2 (FGF2), a key factor in cell growth, proliferation, and differentiation. This antibody, produced using cutting-edge technology, is highly specific and sensitive, making it ideal for use in various research applications, including immunohistochemistry and ELISA.FGF2 is a crucial growth factor that plays a significant role in processes such as wound healing, angiogenesis, and embryonic development.
Dysregulation of FGF2 has been linked to various diseases, including cancer and cardiovascular disorders, highlighting its importance in biological processes and pathology. The FGF2 Monoclonal Antibody allows for precise detection and analysis of FGF2 expression in cells and tissues, providing researchers with valuable insights into its functions and potential therapeutic implications in various disease settings.
Product Name:
FGF2 Monoclonal Antibody
SKU:
CAB22448
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method:
Affinity purification
Gene ID:
2247
Clone Number:
ARC51103
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FGF2 antibody (CAB22448) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
