The FGF16 Polyclonal Antibody (PAC013454) is a valuable tool for researchers studying the role of FGF16, a member of the fibroblast growth factor (FGF) family, in various biological processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications.FGF16 is known to be involved in cell growth, development, and differentiation, making it a key player in various physiological and pathological conditions. By targeting the FGF16 protein, this antibody enables accurate detection and analysis of FGF16 expression in different cell types, offering researchers the opportunity to further explore its functions in areas such as developmental biology, tissue regeneration, and cancer research.
With its ability to specifically bind to FGF16, the PAC013454 antibody is a valuable tool for investigating the molecular mechanisms underlying FGF16-mediated signaling pathways and exploring its potential as a therapeutic target in various diseases. Its application in immunology and cancer research makes it an essential component in understanding the functions of FGF16 and its implications in human health.
FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.Protein type: CytokineChromosomal Location of Human Ortholog: Xq13Cellular Component: extracellular region; extracellular spaceMolecular Function: 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activityBiological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; metabolic process; organ morphogenesis; phosphoinositide-mediated signaling; regulation of endothelial cell proliferation; regulation of MAP kinase activity; regulation of phosphoinositide 3-kinase cascade; response to temperature stimulus; signal transductionDisease: Metacarpal 4-5 Fusion
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]
