FANCA Rabbit Polyclonal Antibody (CAB7671)
- SKU:
- CAB7671
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | FANCA Rabbit Polyclonal Antibody |
SKU: | CAB7671 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human FANCA (NP_000126.2). |
Sequence: | MSDS WVPN SASG QDPG GRRR AWAE LLAG RVKR EKYN PERA QKLK ESAV RLLR SHQD LNAL LLEV EGPL CKKL SLSK VIDC DSSE AYAN HSSS FIGS ALQD QASR LGVP VGIL SAGM VASS VGQI CTAP AETS HPVL LTVE QRKK LSSL LEFA QYLL AHSM FSRL SFCQ ELWK IQSS LLLE AVWH LHVQ GIVS LQEL LESH PDMH AVGS WLFR NLCC LCEQ MEAS CQHA DVAR AMLS DFVQ MFVL RGFQ KNSD LRRT VEPE KMPQ VTVD VLQR MLI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FA; FA1; FAA; FAH; FA-H; FACA; FANCH; FANCA |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 163kDa |
Observed MW: | 163kDa |
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.
Purification Method: | Affinity purification |
Gene ID: | 2175 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |