The ESR Monoclonal Antibody (CAB22181) is a potent tool for researchers studying the erythrocyte sedimentation rate (ESR), an important marker of inflammation and infection in the body. This monoclonal antibody specifically targets and binds to proteins involved in the ESR process, allowing for accurate detection and analysis in a variety of biological samples.With its high reactivity and specificity for human samples, the ESR Monoclonal Antibody is ideal for use in techniques such as Western blotting and immunohistochemistry. By targeting key proteins involved in the ESR pathway, this antibody enables researchers to study and understand the mechanisms underlying inflammatory responses and infectious processes.
The ESR Monoclonal Antibody is a valuable tool for research in fields such as immunology, infectious diseases, and inflammatory disorders. Its ability to target proteins involved in the ESR pathway makes it a versatile and essential component of studies aiming to elucidate the role of inflammation in various health conditions. Whether investigating new therapeutic targets or examining disease progression, this antibody is a valuable asset for researchers seeking to deepen their understanding of ESR and its significance in health and disease.
Product Name:
ESRα Monoclonal Antibody
SKU:
CAB22181
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ESRα (NP_000116.2).
Sequence:
SPSP L
Tested Applications:
IF/ICCELISA
Recommended Dilution:
IF/ICC,1:50 - 1:200
Synonyms:
ER; ESRα
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic side, Golgi apparatus, Nucleus, Peripheral membrane protein, Single-pass type I membrane protein.
Calculated MW:
66kDa
Observed MW:
Refer to figures
This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain.
Purification Method:
Affinity purification
Gene ID:
2099
Clone Number:
ARC55745
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunofluorescence analysis of C6 using ESRα Rabbit mAb (CAB22181) at dilution of 1:100(40x lens). Blue: DAPI for nuclear staining.
